脓毒症相关性脑病的检查和治疗最新研究探究

　　[1] Singer M, Deutschman CS, Seymour CW, et al. The third international consensus definitions for sepsis and septic shock （Sepsis-3）[J]. JAMA, 2016, 315（8）： 801-810.
　　[2] Towner RA, Saunders D, Smith N, et al. Assessing long-term neuroinflammatory responses to encephalopathy using MRI approaches in a rat endotoxemia model[J]. Geroscience, 2018, 40（1）： 49-60.
　　[3] Zhou TY, Pan TT, Qu HP. Pathogenesis and monitoring methods of sepsis associated encephalopathy[J]. Chin J Crit Care Med, 2015, （12）： 1083-1087. [周天昀， 潘婷婷， 瞿洪平。 脓毒症相关性脑病的发病机制与监测方法[J]. 中国急救医学， 2015, （12）： 1083-1087.]
　　[4] Molnar L, Fulesdi B, Nemeth N, et al. Sepsis-associated encephalopathy: A review of literature[J]. Neurol India, 2018, 66（2）： 352-361.
　　[5] Mai LM, Sposato LA, Rothwell PM, et al. A comparison between the MoCA and the MMSE visuoexecutive sub-tests in detecting abnormalities in TIA/stroke patients[J]. Int J Stroke, 2016, 11（4）： 420-424.
　　[6] Liu JQ, Zhang ZL, Kong DQ, et al. Application of montreal cognitive assessment scale in the screening of sepsis-related encephalopathy[J]. Chin J Gen Pract, 2012, 11（9）： 680-682. [刘加权， 张自立， 孔德全， 等。 蒙特利尔认知评估量表在脓毒症相关性脑病筛查中的应用[J]. 中华全科医师杂志， 2012, 11（9）： 680-682.]
　　[7] Chaudhry N, Duggal AK. Sepsis associated encephalopathy[J]. Adv Med, 2014; 2014: 762320.
　　[8] Han JH, Vasilevskis EE, Schnelle JF, et al. The diagnostic performance of the richmond agitation sedation scale for detecting delirium in older emergency department patients[J]. Acad Emerg Med, 2015, 22（7）： 878-882.
　　[9] Han JH, Vasilevskis EE, Shintani A, et al. Impaired arousal at initial presentation predicts 6-month mortality: an analysis of 1084 acutely ill older patients[J]. J Hosp Med, 2014, 9（12）： 772-778.
　　[10] Teasdale G, Maas A, Lecky F, et al. The Glasgow Coma Scale at 40 years: standing the test of time[J]. Lancet Neurol, 2014, 13（8）： 844-854.
　　[11] Donato R, Sorci G, Riuzzi F, et al. S100Bs double life: Intracellular regulator and extracellular signal[J]. Biochim Biophys Acta, 2009, 1793（6）： 1008-1022.
　　[12] Yao B. The changes of S100 in serum and brain of rats with sepsis-associated encephalopathy[D]. Central South University, 2013. [姚波。 血清S100在诊断脓毒症脑病中的意义[D]. 中南大学， 2013.]
　　[13] Yao B, Zhang LN, Ai YH, et al. Serum S100beta is a better biomarker than neuron-specific enolase for sepsis-associated encephalopathy and determining its prognosis: a prospective and observational study[J]. Neurochem Res, 2014, 39（7）： 1263-1269.
　　[14] Zenaide PV, Gusmao-Flores D. Biomarkers in septic encephalopathy: a systematic review of clinical studies[J]. Rev Bras Ter Intensiva, 2013, 25（1）： 56-62.
　　[15] Sweis R, Ortiz J, Biller J. Neurology of Sepsis[J]. Curr Neurol Neurosci Rep, 2016, 16（3）： 21.
　　[16] Streitburger DP, Arelin K, Kratzsch J, et al. Validating serum S100B and neuron-specific enolase as biomarkers for the human brain - a combined serum, gene expression and MRI study[J]. PLoS One, 2012, 7（8）： e43284.
　　[17] Zhou SJ, Bao JH, Wang YP. Clinical study on prognosis of brain injury after cardiopulmonary resuscitation assessed by serum neuron-specific enolase and acute physiology and chronic health assessment scale II[J]. Chin J Neurosurg, 2018, 51（2）： 124-126. [周赛君， 鲍剑虹， 王逸平。 血清神经元特异性烯醇化酶和急性生理与慢性健康评定量表Ⅱ评估心肺复苏后脑损伤预后的临床研究[J]. 中华神经外科杂志， 2018, 51（2）： 124-126.]
　　[18] Zhan LH, Cai QY, Wang JL, et al. The relationship between serum neuron-specific enolase level and sepsis-related encephalopathy[J]. J Crit Care Inter Med, 2013, 19（2）： 106-106. [占凌辉， 蔡秋雅， 王金领， 等。 血清神经元特异性烯醇化酶水平与脓毒症相关性脑病的关系[J]. 内科急危重症杂志， 2013, 19（2）： 106-106.]
　　[19] Feng Q, Wu L, Ai YH, et al. The diagnostic value of neuron-specific enolase, central nervous system specific protein and interleukin-6 in sepsis-associated encephalopathy[J]. Zhonghua Nei Ke Za Zhi, 2017, 56（10）： 747-751.
　　[20] Zhang LN, Wang XH, Wu L, et al. Diagnostic and predictive levels of calcium-binding protein A8 and tumor necrosis factor receptor-associated factor 6 in sepsis-associated encephalopathy: A Prospective Observational Study[J]. Chin Med J （Engl）， 2016, 129（14）： 1674-1681.
　　[21] Berisavac II, Padjen VV, Ercegovac MD, et al. Focal epileptic seizures, electroencephalography and outcome of sepsis associated encephalopathy-A pilot study[J]. Clin Neurol Neurosurg, 2016, 148: 60-66.
　　[22] Ma YJ, Ou YP, Guan XD. Quantitative electroencephalogram assessment of brain function in patients with septic shock[J]. Natl Med J China, 2016, 96（3）： 195-198. [马玉杰， 欧阳彬， 管向东。 量化脑电图评估脓毒性休克患者脑功能的变化[J]. 中华医学杂志， 2016, 96（3）： 195-198.]
　　[23] Gilmore EJ, Gaspard N, Choi HA, et al. Acute brain failure in severe sepsis: a prospective study in the medical intensive care unit utilizing continuous EEG monitoring[J]. Intensive Care Med, 2015, 41（4）： 686-694.
　　[24] Yu M, Zhan Q. Application of neuroelectrophysiological techniques in sepsis-related encephalopathy[J]. J Neurol Neurorehabil, 2017, 13（2）： 80-84. [余敏， 詹青。 神经电生理技术在脓毒症相关性脑病中的应[J]. 神经病学与神经康复学杂志， 2017, 13（2）： 80-84.]
　　[25] Pierrakos C, Attou R, Decorte L, et al. Transcranial Doppler to assess sepsis-associated encephalopathy in critically ill patients[J]. BMC Anesthesiol, 2014, 14（1）： 45.
　　[26] Wen M, Lian Z, Huang L, et al. Magnetic resonance spectroscopy for assessment of brain injury in the rat model of sepsis[J]. Exp Ther Med, 2017, 14（5）： 4118-4124.
　　[27] Sharshar T, Gray F, Lorin de la Grandmaison G, et al. Apoptosis of neurons in cardiovascular autonomic centres triggered by inducible nitric oxide synthase after death from septic shock[J]. Lancet, 2003, 362（9398）： 1799-1805.
　　[28] Sharshar T, Carlier R, Bernard F, et al. Brain lesions in septic shock: a magnetic resonance imaging study[J]. Intensive Care Med, 2007, 33（5）： 798-806.
　　[29] Bozza FA, Garteiser P, Oliveira MF, et al. Sepsis-associated encephalopathy: a magnetic resonance imaging and spectroscopy study[J]. J Cereb Blood Flow Metab, 2010, 30（2）： 440-448.
　　[30] Finelli PF, Uphoff DF, Li Y. MRI manifestations of septic encephalopathy[J]. Digest World Core Med J: Clin Neurol, 2005（1）：23-23. [Finelli PF, Uphoff DF, 李源。 脓毒症性脑病的MRI表现[J]. 世界核心医学期刊文摘： 神经病学分册， 2005, （1）： 23-23.]
　　[31] Oddo M, Taccone FS. How to monitor the brain in septic patients?[J]. Minerva Anestesiol, 2015, 81（7）： 776-788.
　　[32] Li DY, Wang Y. Diagnosis and treatment of sepsis-related encephalopathy[J]. Chin J Appl Clin Pediatr, 2017, 32（6）： 404-408. [李德渊， 王杨。 脓毒症相关性脑病的诊断与治疗[J]. 中华实用儿科临床杂志， 2017, 32（6）： 404-408.]
　　[33] Ji MH, Xia DG, Zhu LY, et al. Short- and long-term protective effects of melatonin in a mouse model of sepsis-associated encephalopathy[J]. Inflammation, 2018, 41（2）： 515-529.
　　[34] Tarr AJ, Galley JD, Fisher SE, et al. The prebiotics 3Sialyllactose and 6Sialyllactose diminish stressor-induced anxiety-like behavior and colonic microbiota alterations: evidence for effects on the gut-brain axis[J]. Brain Behav Immun, 2015, 50: 166-177.
　　[35] Li S, Lv J, Li J, et al. Intestinal microbiota impact sepsis associated encephalopathy via the vagus nerve[J]. Neurosci Lett, 2018, 662: 98-104.